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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ee3ed4ec392b376b76a9b5318c5ab7163ee4a0338640456beedfc3cfe85f570' 
  AND token = 'Ay4VPV8i7Zso1C1OWAW7s/uCz+VYFk/4Oi8TrEtSPNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}