SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb95f287a0819ae8d4e3737fb35d7c89b388cc138e88773e290a875f90cd6153' 
  AND token = 'MUap9k73+UIB69m1Pp+sX0chxCmnl8fdSYeZnMCHSLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}