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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b9ea79ce0b1a7631e6a3dc25addc9bad3debc1fb07301eba0813196ce7cf26' 
  AND token = 'eMDDEXOfOM/Kvh7fJn6Yf03PRX8vYCx3gczRwlLJspA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}