SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143d69fd13ee93eb2b720be18bf562de55ee10920a58ebd894e2f91d90158811' 
  AND token = '4s7j/JBIlEEpYDnbfDYXY/Cy+qBxjQA+B5oBJ/VZdCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}