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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8c7d0b9def838e307e0efb708ade786ef6c7fdc924d5ee1c7f984804a9d1d9' 
  AND token = '2sA0MJkKjINyf8HouWdfI9nVQMcRRjz8Z7iU7ohCSXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}