SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94918e3e674a85e4c46e2ecc1d95b56fbc066cf4e2477300b459ddc4b0186aed' 
  AND token = 'r/IAbEXhdK+OB+kgOPyCGZfJ5EHHQWskrCHnPpwkeYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}