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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8248b7fc005de9ab6f16ce21274e160ff5edb044ae701291f18dbd50e141d43' 
  AND token = 'H80qiKPYkrVsNDLv3YutJBAnFNCD+a8q2vtCy6V+K/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}