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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa21e390ddc6ddb5c4dc4d3067e42c0b3b2da25bb3846bf304e31c77538bb8e' 
  AND token = 'Mc+8QquqhZscn+wkEnNgOcpHvFAvhOcEzu9tCVil8ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}