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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bebdc320b5b573279acc23e2568e6aa4f62516dd25b0bc644c25b7551029e101' 
  AND token = 'j/6wiUQT2uD4/iuX07ULb7GSmmdfAxO10LIr3Fv9yZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}