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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b54020a224c086038db76d110e8cc3204e3d4138929e4c245bc6ef0754bd1d1' 
  AND token = 'fP95/IDxexC09Eef+RnEtU+JDKtMHK/ajyCQKNJ9dZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}