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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11322262f5086c11086d72bfa2e91fa01a4ce54c31a5b3c38c7f7b791a12b89' 
  AND token = 'GX0/VEZd9QkzZDUzWDdxHkMzt/8lfULmBYoG1pAZGoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}