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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76373447d3b3ab32e8d18f88f2b9b36749c67a6ae3c44b3fef1bae459ff3efd5' 
  AND token = 'DQPd0Gus8Y2UcCF4+qgyYvvUjeaEGsun8yCbxJJ/5Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}