SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19fddec628e8c952beece19e8844da41f8f098a20d5c23f36818b820d4ffbff9' 
  AND token = '2HFolmN6Efz/2HtsTc06li++TqRim3UsyRv1a1aUEno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}