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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd211bf1e83fc190810cb63f7736c8c1e321d69bcb06f7998fec49a32ad009c41' 
  AND token = 'hwo/mPQCzGIscK/bJzUW8KKfNh82v4KgNI2nsZa/dwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}