SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f2da224565ea1072f08281c0f34b1c5e9dc12499cfb7d9afb7a2639340cac6' 
  AND token = 'Nx3scdRGnh7tgIdecPmYJErq7ImeEx5wB4mayJ+sCpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}