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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f56ff18cff7160ea800339e71d30d932de155046b7c6ab21e45891c21edc35' 
  AND token = 'VUU6enOcv+6GfxpHL3jfUos2P7hv3lEFC44PgQAA05M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}