SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227a372a05e5e47a936059f0bd2bbc8103da9550e57fe385a3080e600972cc08' 
  AND token = 'ASnsjB28MA9Y8E7irA4lnY2h5Jb6GAdsPUs+R0kBINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}