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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1088290e8e6321be6b169db9083cf703a088a6463cc3b286a4542ccece337b' 
  AND token = '/HfRcoEUJJ52rg4oe+I5+VaJO7KteBRwJC0LorK6Wl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}