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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1f1e9cc44f0bdd6f6847bf8c90590e9a4f6d873d504f70188f70e4b3d1c9ce' 
  AND token = '8yIZf805yP5BPJXiYvrabrF1amiZrujtfKgMSr0pviA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}