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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ae3da01cf241e9cbd5a669b5858d5406d927bc2424f2c589be3ad9a57fa499' 
  AND token = 'PYjIi7dfViJUXTWdbeWGy4z/e8ku+sWSfNsnFdFALyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}