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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a81089e9a16a2f1e2a6fae4072d689cefd8cd9773ca4ce3ed35013035c00def' 
  AND token = 'xnPkaPsE78/8mij8YJtKA4QegODEoALB326HZCaVS1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}