SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ff37449c7d20c61baa0abb0bd5ddc6aa5a34036ad4f8c64672fde014f117db' 
  AND token = 'TAMzsANudA0Fnqiqcf1uV6eU08Jf5ad7HLW3CxoxrEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}