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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5c7e9d041c430dd0a309059449ba91eb9dd8ecd6c5d8eea85ed3509a91623e' 
  AND token = 'yKoB7dV6aZDnflTIzFv6JZ20Rvo+EECrCmCXiRJh6Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}