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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '769e618c80389b28b7081292ee458d4987e641c34b06b0215068d7ee30faa4a5' 
  AND token = 'pgxPD7x/BQ/xO6GubFS6j7Gy6rWnXawYO0rANU2LG5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}