SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2855da3da15281dcbe01c633d0ac78c93f2a33271efdab0cbea915728ccc67' 
  AND token = 'VNhcRh9CPU8XA5TV1Y3NWfeeW/jUdoakOZSv6PfQb2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}