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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a34c2341af56389b1ec8b3fe93a9d21caa5deb5ece022face6260d7dbe2dc99' 
  AND token = 'AMoDcRbhOQT/mwZxbGGb/QsS+ePOM6AtcmBt0U6jfVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}