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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f86a9e61e5fa3685ab8b8ac48f54bff5022ce8930d1ca4efdd60c64338ed4c' 
  AND token = 'fA4XhgVcduKyI19v/J9mG7K6x/nIiWyRGyWjnhn6Y/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}