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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886e68a55a37c1a514052a458bdb8ff31a8438f8b2489d9a35c7c5a09acacab8' 
  AND token = 'NpEEr/buSEYwc8enlfisce92F0F093X8umQ2Op0sj04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}