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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d62e3688c45d5698fa3fbef7ca83640e87269b49a8fc233fe0811cda63a0740' 
  AND token = '8HLdVS5COnSw/j2DuirlyzcpbsYfmClzZx05YedmtxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}