SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35943b0fa0c924ee0fd46c3157c81b36e6ddd423934128ffda05870c01c15425' 
  AND token = 'dHNqacWwKIPuLAU2U5tK4cimaYp3SVpsXQfxh4vlkHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}