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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b661bc5075ef390cb94e81cf155fff5511dd616333fe94110a12698ffa7dc0f5' 
  AND token = 'ZmYjInuvBrfYFeGq+6AiON1EW32xLA0cOFnKieYKnkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}