SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acbf803176b62622cb2f6749db392f05d32a393eebca553f96125845089d8e63' 
  AND token = 'jAbe6LRCP0ddPPlw8soLd4aAhOsh567gdmpcm1Bee6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}