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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def116e7122e32ae2acc3dba9c43cd9955b2c46d213d20030e665abcf17ddb39' 
  AND token = 'rw5J63PiRpLmcWZZrzfAqUYy1gtl6kBQ5bq7MVFNVX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}