SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2ceb874c06af83dab0dd616e9832f9e0fb79c7e85eee64a021109b3694ada3b' 
  AND token = 'JOG1j8qz+g8STj22w6t/SIAUgiG5aDmppAEFR3IF0aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}