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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef83c938e7ec660718c864dfa4cad38f9494cf8ad219d21aa7f08ef5e525701' 
  AND token = 'SCmg4MDWw3eRTK47kR/SuSI0EfgE6f1NmunDg/P+yDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}