SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d695b605fcafad1600d8023ca27550f468ece0b8b82e55cb85b70fd540aa479' 
  AND token = 'HstQx1etZsLqsEVs0uKcasL1qjRla+tMQxTaX+dwZpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}