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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d075b06896603ea09fb8051c32929358ba8cc4458fe097a36cf213dad61c90' 
  AND token = 'Q46X0cuHow9cTlbKJAwjQLr87uPh8z3wVW+Qh0EL/cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}