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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1171f2757d78ba55abd4a396a69ebc3efe302a1b5e08d6e63018c1be17fde860' 
  AND token = 'dYSsCldxr63D2JRC+2XAP4839kxIQTm+LlE1T0GRekA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}