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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7f3ee018e7c6d9a00589574ba4b9282ff665b35b06911408896cb87aaf6009' 
  AND token = 'sOcrs00qGbXe8Zzszj0mn4btddzLEBrObRj2vJkCo9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}