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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c5237f171f4bb3f8ce8309c7523bb16448ecc9ef4dc4a363b024b3a59900d0' 
  AND token = '2Aa32SUJy+A6/xrsMTUiGEhMnidh3fjeYJ38lf0cJJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}