SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4dea7d384dead6dc2fffa0f95c0665ff25e5d0b2bbae8f9b9997e111308908' 
  AND token = 'THOjKUSwQUdl2bzsEYFiHsnyk8VAaQ6+F06AbCj0zFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}