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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c6b8d1754a6ea7b28143afb3d7d280277516d0906fb7238d6031dd783d7f991' 
  AND token = 'DX5xxyGLHcIGGQbBe40SVLSTD8DmQRPnNSzC9nCLY+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}