SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db2b8669fa75a967f13f705aff3263cbe40d843cc77681e6623293fbd71495bd' 
  AND token = 'VwKN1yi+Ay4ZfS/EfT/T/g27TM+BWD68k0CsRpCV0hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}