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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272047fe77007f4c3b723c7e8db988d3a42fe5d6734a574f0c8604f925bcbe46' 
  AND token = 'RXnrpO8oG8CyD7bjI7LwuawycX1BqWL7UWGiFQ8lZGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}