SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f76b378db10490f1530209f38ad1c2db031de1c5f68f855d5b2d8b995566a944' 
  AND token = 'GrN6m1qhjpYfoaGBRm1MYGEcO38b05NhFaoFqb9Ysd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}