SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e72984aca7a60934bd589833bcf2cdfe0cc78db74fbdb92e7810426ef6e330' 
  AND token = '3Cl0t9XpSQXhKfd3UaT2pF41YoI104KsyhyjzFKWoUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}