SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d93bdbea29bfc7ab109594a33acd7f9eac046d1b0bcd5aa86396f68e32d1496' 
  AND token = 'VygQ/Voyun+nvO0K7d9Y6gSB22bmhc/S2aSJwCFmakk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}