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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81480bc02f76b77c4d30c90983f23c786aff7a3f5625a3ba34a1347a46016d6' 
  AND token = 'Mhx2odLBe0LRZyVh0LvbiRiwNb72aqWmAMz351O0QbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}