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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c3bce19f9b090d3021bf5c84f2c1fc781e90b2dd4dab9b4269235e5d2894cb' 
  AND token = 'wkH9099HcIUdP8oEDCAkwyQWdqZSb1zYtUMQNrntFX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}