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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e205f78e8b354abb79656b1152290dd684ae9f15b0b9c69cd67134f03ebb732' 
  AND token = 'hiEMtDuzrQFxlAfeTc8Ka5vBXK74A+xbXxS/ONd3TPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}